Guruvayur Railway Station is on the east of the temple which is connected to the Chennai – Mangalore main line at Thrissur. Thrissur Railway Station is the nearest major railway station, about 29 km from Guruvayoor.
Guruvayoor is well connected with other parts of the country by road. Both KSRTC and private bus services offer interstate bus services to almost all major cities in south India, including Palani, Madurai, Mookambika, Ooty, Coimbatore, Dindigul, Salem, Mysore, Chennai, Mangalore, and Udupi. National Highway 17 (NH 17) passes through Kunnamkulam about 8 km from Guruvayoor.
Kochi International Airport (NedumbasseryAirpot) is the nearest airport, about 80 km from Guruvayoor. Calicut International Airport (Karipur Airport) is around 100 km from Guruvayoor Sri Krishna Temple